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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd414c448449c2400cf550876e06314bc24b291e3dc7b778c64aab7d7d021165c' 
  AND token = 'y476Umh/ZqeQ0LAcMSeDX8f+ieZI19vUJhXn6DlcS8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}