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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8403ee55a15813d362228309cbf2d701aabcf73d0a3b3646806540227778db3b' 
  AND token = '6M1WxEQF21iW5VSkM3Sn9YYcFUl9QbrxraAxPNKi0cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}