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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb75ffcac882dfd9cbe8cca83c4571c626bfa0c61c8f0a1867477b525056012d' 
  AND token = '6L79aCi4Y7tSTtpuq6OnPRTHuITlYHaoDTaollDGZAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}