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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f921d41fed08bff3431e531b2d8be3f7cdf0a659a1049c063249ba7dbdb9920' 
  AND token = '1vNPZiD308aRSSY4zqrcFZxZ5TKL+ehyUhZGcQKa3Ps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}