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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43667451954e27513eef4f78832846116befd10a59da48a77890be6b2034152a' 
  AND token = 'pwp8FyZ6ahdKrBC8QuabpFg9hNC9Bs6bitvApMH611A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}