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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b72693857b14ebdff7de87cf9c4a474ca145a581781f91de013d988f55e47017' 
  AND token = 'cAUxfxqQT+548wRDFcYPjrb2j6nTnWhCDIq+5kkVwsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}