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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc23f112a2edf48e57e094f472d9b18f2b0486438833e2845dc89560a2e4bdc8' 
  AND token = '+ZB2ucnYLpEOk8BxDE658DqrVbjvpEUHlTGuZyj5+3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}