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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ee38000de13bcc3532186591b6ab2034f469c3441ee87f40e1456892cf9ea48' 
  AND token = 'qHLRygTvLzoNZg+mJg37L+Pg/ISSquAewzE8RdLbZoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}