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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3c5931f062654a3b67613620ba48df6f6c1f56e7df21269b2d30a3af011d3af' 
  AND token = 'fgUF+eKZKIOjnd16+4iBIcn1TFdvMq2jDr9dfVsnlLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}