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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f806d826afdcb4d12ae27b686f2b5f5645e4afc2e20a0532e4946b11d0250300' 
  AND token = 'EMfd23D4HExch2vKw4SRKM/3h0MXi0VC1h7O5fzABXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}