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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'def50af8c23c4fc6ab72cc77c664dfb0dce94e389eb0a7f7aa653d0a31e935cb' 
  AND token = 'ogtgPhrDwE0gsI/fudvp3W1DkmiUDIix3u3lrIkL1xM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}