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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77f4a3c3fc4f1def5671073b795751940ee26b63ed41622b32dbaa2613513edc' 
  AND token = 'mGG2hA0cTNymSPEnlB0MZheUUS/9Y50ea8Y0OsG8MBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}