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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5daf5be9acd8b694d5c8168d5c3dc69c1a2170011a1c1a7a330f2f3d31e2cb28' 
  AND token = '5GX64NflwDl+dwZj0/giGWojBFGmFEXppr7Md+Rk7Rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}