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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f8027ed6b8b2a36623682fbeb13339f2c4229d6c09c83ac2aacd9231c3b9e2f' 
  AND token = 'ByFq15IXL9YQpNN/zA3x0iW2k2Dw7/Oka3vF9rALtsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}