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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '220b013eb4a7d92ac019919aba851de537e0f2b478cbba27539bdc1471e2a1de' 
  AND token = 'pOQ5YCalrm4dh3iyD86J66re7Sorbu+m8/ZTCKvy2L8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}