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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b78179e1066e455bd374e120e3e9bd5d04dc40e4020913adc0fb5725e6a1b419' 
  AND token = 'MTutd61Cb5dIqLtTHycoU/es0McN2kNfNvwT8PgA6/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}