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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8917648b1012bd8977ddb2d4a3bf7866c04293c41f081ba781b49170fb95eb14' 
  AND token = 'W+I6zKE78c0xMmUPju2C7dX2r7GChm8t6dAMspE7QfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}