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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8137307213395bf2d35f27d2b3757312b0964ef3ebf4af0b77365228657fd351' 
  AND token = 'nWChYll6/u1lzyKNBS2H5FiEMvSWyFIUtzh/8+nXITQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}