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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '746fb037f2eb0c414d7b9d3e192547956942353f1fde1b74cf03dbec23aa0003' 
  AND token = 'PMYfSbvRBrHRIPJ4itrq2R6ZeLZCKtKujFQbkuX8+OE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}