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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54f590e40ebbdd682dd3efafd6a03027bf097d17ac78794a5a56583e3dc7314a' 
  AND token = 'VVQ7hJots6MUXtLiVyF1SXxRUqq0x43Mbkwyg4U+noA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}