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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eeeab36c83420d0b4c610dba1cb57951d6c6c49a946d01029749c53840824ce' 
  AND token = 'W2GyASaIMaCTNmJrxvrmJG4/jE63fOViOnJMr9KtfJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}