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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1a211339a4c52c038cfc53de461dcf268b5d9899237b00a016f6151828d0006' 
  AND token = '8C2DY/h2jxLQRGysgeL7VHI/e3IM93BvDQj40g54jsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}