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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '469ae82369393c2b802677968c0c0b77f5664e3facea1aeba8b99b13a4c0d386' 
  AND token = 'WWLQ9k8Ao9J+Ox/Wia4I3le+TGyzva2+8c+h6IKc/WI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}