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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c72559c244b26d66b75490504fca50a0fc9a4f0dbcf0e4050ffd6da7b07e7fd8' 
  AND token = 'CNUybSyIs+nvcVkIGOw++zOJlS8TJV6ye9DDUtFRoLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}