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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd16deda8cda43210de1c1b07dee5c1b61f0b528402813552f9ed4095b1c6c95b' 
  AND token = 'kWH6NcQnbcdSnJx0g7mMwKrFs9HhxJahFNxY7WVLxdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}