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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44e3636d19abe662ad84bd8c0bc10580a889c0ada8159ea4c959c5ea100ae7ff' 
  AND token = 'JzwT+a+Vnkh8vS/C35QeTBD9n/8YoHZO9B3Ix0w9uso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}