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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d39145c2475dbe777c726bbebab269f46d1b4ab6df46b8c3c58f56b220d6ae4' 
  AND token = 'DFmTE7hDO5bHBJuySEbublRxinRwRf0+RzlU7UrAsqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}