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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7744c206eef271457b5503a086ccfd36fae87919656757b0564ce26629bbbd8' 
  AND token = 'A5Vq+sWRqt5bN8z7GuLkc1ZkZBiJ2uL7zWRmic0aonw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}