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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b61c0e5e5e6a720734ab18247f51ef42954d4ab72405404bb22b6f26735defe' 
  AND token = '3azmJFn8C1F60pNz7n1xXTg+GJicq+MdicXFGdBfPko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}