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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb2d2a9e9f2fe32d77443c53e559c9761c59dd37e0b49bfcd34c03b4a424cf00' 
  AND token = 'By6MyksYANWl76o5whTaaoSMUp+rRijoU46vVNMXF0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}