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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61b99f605873cd57201636aef549b0885e1063e294c35b5aeb813f54d34e8ce8' 
  AND token = 'uvzOf+6O3M6T7O/Y/BRCt6r236HmXrvUN/IhwINLjYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}