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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c08af51181f247382160a06ebacab475188d71c2f53602131eee1aa77029eaa' 
  AND token = 'h+8zHcrvgiJ1E3M49FsB6gH23O0c4HFrVjUT0si9MhQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}