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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c9048d57cbb6dadf31d7775b9060c252d8dcc8b7ad3a906a0d614a24e1f7443' 
  AND token = 'smWFhM+g5iJ1TADEU5PpAAEe9yax4EJJTAFJcWVs0d8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}