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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c38b7b24a3dae59b017e578dcaa0ac9ef3420b017ff20d14f032fac53b0c553' 
  AND token = 'E25s4oqs3RYnT7Dr9S+BFJj4Ptgr89UmS3X8bqSttrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}