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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e9f61102f132b17041726877cb7abd5617c14293f677c28061b2aee3ea2219a' 
  AND token = '95editQ4aD/QN/WAfLofNbd6yE2vngAKCOKO3cSiglk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}