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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55a784d9a63c9aba5263f49cf52e4dd74a1bf64c6b001436ca417bb73d3ab564' 
  AND token = '7qNyhzBfiNLf8NfEHYNicOuj78hOiEvnXdPEc/xlm7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}