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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8487bc59581332efa85f213b0614983fa2ac4210327b266d5177df62d312c443' 
  AND token = '2CUAd4idLnm1paq4xtk+QQS/9eo2vEps8+Ja/QyT+YY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}