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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39ebd6bf2e3149dbb8e159de6b08e7c1775ca3f336922678b22999977964d297' 
  AND token = '/S8ngR4uR729ux2037Gr12PDwW6zZF7X5n+wlhNDa5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}