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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0c5c00934193e7160ceae87e08b4b9a21146b085187bb5c160f31ed215967ca' 
  AND token = 'PuMW0C8lw23m5QprkvSqxT/JqfOzBcww1zqooyCaiPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}