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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '654d6b6cb9f05990dbee28e7b7c2fe6ce3e52cdd69c6d039c205c1bd41de58d3' 
  AND token = 'r1JT2FxxFvKUAyrb/eY++njRQRpvLP7jwnE6dI5PtMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}