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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9e9202bb5425c16e7a5907a648a77f226fc7548b956e82cd64e1176819a5f28' 
  AND token = 'nopZKJfQI/Ai0y66RalYXoWb/tL0ofTgGaJ0fK8lCvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}