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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '506f3c9c3698e438e70fb7a5d6c6d0d50722c42ae368d6fe7fd1ec6e01595235' 
  AND token = 'T00+bPUJ7+s3m8NOyX5bVg+5lkAVILv3IuPmiVGRsC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}