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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51c5f50f15db398f062bb907fd4efda3d36e04fac0aa1b18bff3d599458f53c2' 
  AND token = 'gD86TNH1ei/81B4d1ZIUTWjW77tgo2HHf7ApRN26ISo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}