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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4984f21013f9db808deb98f47fb0578cb10606e79aa7e252fdf405c539ddfe5' 
  AND token = 'i/Z+3M26jEZZRcSEMK8nKD0xngc8IJjpGUtNc3UU0RE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}