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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd63396e8a554ca9932775e1c5091e51262cf6b16cee70f2a4a5b33d308154522' 
  AND token = 'v2EVvlpY4bV8tL1Io3EuXSM+7kJUj8vEBiFkiH15OXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}