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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a227144c923106c9714b736d6ab2acd5d9bedb36e6c6a8b49dee13e2bf99220e' 
  AND token = 'fl1hqLCdu+AEaPtA6TPEIst5s9a8nnkv/zbXT/zbXB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}