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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '124bc76f0592ec7358d2bfea0e400fb69beb077bf75cfb746af2934f10c44bfc' 
  AND token = 'KtBUAIia7ZrmL3rEXZRx2EInLACr+Afa4PgGVKUvJZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}