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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84b1df17222cc6bc7010b3bb0cb8433b6ca75222e8265b518599aad68c342027' 
  AND token = '10jWl1N6G30UrIaEnaIDSfWTGE4OlopaewTWpqcgBKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}