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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '261b60c30146ae49f43a4509b90da0c81e5bf07afb9dae123f178b2cc811cf2c' 
  AND token = 'htfniA3GDgvt2hnRVasK2LAd5JWTakL3ZhpL7eORVIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}