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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd733bdc25e604fac09de9b41723f3f499fc0c3145107033057330acadccd16a' 
  AND token = 'l0Ivry/XRz6JV2kDNDL/LMa6nF3CCr4qHLx8ADD6m/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}